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They decrease appetite by increasing serotonin or catecholamine -- two neurotransmitters that affect mood and appetite. Phendimetrazine and Phentermine are
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Phentermine International Programme on Chemical Safety Poison . It may also slow down catecholamine metabolism by inhibiting monoamine oxidase (Hardman,
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For example, as with amphetamines, Phentermine inhibits the reuptake of catecholamines, thus increasing the level of norephinephrine in the brain.
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